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?+?What is ExperimentBank?
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Welcome to ExperimentBank! This is an online forum for the submission, discussion, and evalution of scientific experiments and ideas. You can register and vote on others' ideas using the links to the right, and you can read the experiments others have reviewed favourably using the links below. For more info, check out the FAQ page. Be creative and have fun!
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?Knocking out Dicer in the brain!
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By RFZ, Section Wish list
Posted on Wed Apr 19th, 2006 at 01:18:04 PM PST
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This experiment is one that would yield a lot of results should it be feasible to carry out, which is why I thought I would post it. I'm sure there are labs that work on similar projects currently though excuse my ignorance, I cannot name them. Without more ado, here's the idea ;
to generate a model organism (mouse/rat) with a dicer knocked out in the brain to study miRNA regulation of gene expression
(314 words in story) More >>
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?personalized medicine
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By sjesslee, Section Wish list
Posted on Wed Feb 2nd, 2005 at 05:49:12 PM PST
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Are we ever going to achieve real 'personalized medicine'?
(60 words in story) More >>
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?Ab Library
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By Amoeba, Section Wish list
Posted on Mon Apr 28th, 2003 at 08:02:00 AM PST
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I propose we create a library of each possible conformation of immunoglobulin possible. It could link genetic code with functional structure, as well as the potential binding kinetics for each conformation. When one has a protein of interest they could compare it against the database to determine what Ab would represent the best fit for creating affinity columns or which Ab would target the structure of interest most effectively. Once the simple comparison had been made to the database, and the appropriate Ab selected, the database would spit out the genetic sequence for that specific immunoglobulin conformation and the researcher could then proceed to create the necessary hybridomas. The potential benefits to this are (to name a few): 1) One could control and design Ab for specific locations on the peptide / protein of interest, 2) There would ideally be a range of binding affinities to choose from which would allow the researcher to tailor the affinity column (or what have you) to their needs, and 3) Researchers would have a much more direct methodology for generating a multiple Ab cocktail for protein isolation.
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?Take the power back
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By a messy ale no gin, Section Wish list
Posted on Tue Mar 11th, 2003 at 10:39:51 PM PST
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The publications that scientist produce are the property of the journals which release them. This information is ripe for data-mining but inaccessible at the best of times.
(187 words in story) More >>
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